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San Francisco pre-seed VCs

A curated list of active San Francisco pre-seed VCs investing in startups.

by Tzakhi Freedman · December 15, 2025


Today, we selected 10 active San Francisco pre-seed VCs from our database, investing in startups.

Our team reviewed, checked, and enriched the list with the necessary data.

Here goes:

  • 7BC Venture Capital, Based in San Francisco, 7BC Venture Capital is a pre-seed venture fund focused on powering the digital economy through AI, FinTech, and software technologies. The firm invests in early-stage companies driving innovation across these high-impact sectors.
  • 8VC, Headquartered in San Francisco, 8VC is a pre-seed technology and life sciences venture capital firm that builds and invests in the world’s most ambitious companies. The firm backs biotechnology and transformative industries that drive systemic change.
  • Apa Venture Partners, San Francisco-based APA VP is a pre-seed and seed-stage venture capital fund investing in healthcare, B2B SaaS, and consumer technology startups. The firm partners with founders building scalable solutions in services and enterprise software.
  • Beat Ventures, Based in San Francisco, Beat Ventures is a pre-seed venture firm investing up to $500K in applied AI and ML companies. The firm focuses on technologies that enhance human performance rather than replace it, supporting visionary founders at the earliest stages.
  • Blockchain Capital, Headquartered in San Francisco, Blockchain Capital is a pre-seed venture capital firm investing in blockchain-enabled technology companies. It supports entrepreneurs advancing cryptocurrency and decentralized infrastructure innovations.
  • Coyote Ventures, San Francisco’s Coyote Ventures is a pre-seed venture capital firm investing in early-stage companies focused on women’s health and wellness. The firm empowers founders innovating in healthcare and well-being sectors.
  • Darling Ventures, Based in San Francisco, Darling Ventures leads pre-seed rounds in software startups across North America. The firm invests with a concentrated strategy to maximize capital reserves and founder support throughout early-stage growth.
  • Diversity Venture Capital, Operating from San Francisco, Diversity Venture Capital is a pre-seed firm that helps underrepresented entrepreneurs scale from 0-10. The firm combines funding, pre-accelerator programs, and team-building support to promote inclusion in venture ecosystems.
  • Earthshot Ventures, Based in San Francisco, Earthshot Ventures invests from pre-seed through Series B in energy, mobility, agriculture, and carbon sectors. The firm supports both hardware and software startups with access to a global network of investors and partners.
  • Euclid Ventures, Headquartered in San Francisco, Euclid Ventures is a pre-seed venture capital firm partnering with domain-expert founders. The firm focuses on transforming cornerstone industries of the global economy through innovative solutions.

We have also put together a list of 110 Worldwide angel groups.

Our premium subscribers can access the list with all of the necessary data, including:

Name, website, HQ location, LinkedIn company page, description/thesis, preferred stages, preferred domains, and contact email.

To view the full premium list, upgrade now at a no-brainer price:

That’s all for today. Have a great day!

Tzakhi

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